Heart disease is the leading cause of death among men and women in most countries. Preliminary research has led to a widely held belief that vitamin E may help prevent or delay coronary heart disease. Researches have reported that oxidative changes to LDL-cholesterol ("bad" cholesterol) promote blockages (atherosclerosis) in coronary arteries that may lead to heart attacks. Vitamin E may help prevent or delay coronary heart disease by limiting the oxidation of LDL-cholesterol.
Vitamin E also may help prevent the formation of blood clots, which could lead to a heart attack. Observation studies have associated lower rates of heart disease with higher vitamin E intake. A study of approximately 90,000 nurses suggested that the incidence of heart disease was 30 percent to 40 percent lover among nurses with the highest intake of vitamin E from diet and supplements. Researchers found that the apparent benefit was mainly associated with intake of vitamin E from dietary supplements. A review of 5,133 Finnish men and women aged 30-69 years also suggested that increased dietary intake of vitamin E was associated with decreased mortality (death) from heart disease.
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